Epidemiologic trends in esophageal and gastric cancer in the United States

      Esophageal cancer is known for its marked variation by geographic region, race, ethnicity, and gender [
      • Munoz N.
      • Day N.E.
      Esophageal cancer.
      ]. In the United States, esophageal cancer accounts for only 1% of all newly diagnosed cancers; however, it is the seventh leading cause of death from cancer among men [
      • American Cancer Society
      ]. Stomach cancer is the second leading cause of cancer deaths worldwide, although it ranks tenth among US women and eleventh among US men. According to estimates provided by the American Cancer Society, approximately 9500 men and 3000 women were expected to die from esophageal cancer and 7400 men and 5400 women from gastric cancer in the United States during 2001 [
      • American Cancer Society
      ].
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      References

        • Munoz N.
        • Day N.E.
        Esophageal cancer.
        in: Schottenfeld D. Fraumeni Jr., J.F. Cancer epidemiology and prevention. 2nd edition. Oxford University Press, New York1996: 681-706
        • American Cancer Society
        Cancer Facts & Figures—2001. American Cancer Society, Atlanta (GA)2001
        • Blot W.J.
        • Devesa S.S.
        • Kneller R.W.
        • et al.
        Rising incidence of adenocarcinoma of the esophagus and gastric cardia.
        JAMA. 1991; 265: 1287-1289
        • Devesa S.S.
        • Blot W.J.
        • Fraumeni Jr., J.F.
        Changing patterns in the incidence of esophageal and gastric carcinoma in the United States.
        Cancer. 1998; 83: 2049-2053
        • Devesa S.S.
        • Fraumeni Jr., J.F.
        The rising incidence of gastric cardia cancer.
        J Natl Cancer Inst. 1999; 91: 747-749
        • Ries L.A.G.
        • Eisner M.P.
        • Kosary C.L.
        • et al.
        Cancer Statistics Review SEER. 1973–1998. National Cancer Institute, Bethesda (MD)2001
        • Brown L.M.
        • Hoover R.
        • Gridley G.
        • et al.
        Drinking practices and risk of squamous-cell esophageal cancer among Black and White men in the United States.
        Cancer Causes Control. 1997; 8: 605-609
        • Brown L.M.
        • Silverman D.T.
        • Pottern L.M.
        • et al.
        Adenocarcinoma of the esophagus and esophagogastric junction in white men in the United States: alcohol, tobacco, and socioeconomic factors.
        Cancer Causes Control. 1994; 5: 333-340
        • International Agency for Research on Cancer
        Alcohol drinking.
        in: IARC Monographs on the Evaluation of the Carcinogenic Risk to Humans. vol. 44. International Agency for Research on Cancer, Lyon, France1988
        • Kabat G.C.
        • Ng S.K.
        • Wynder E.L.
        Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia.
        Cancer Causes Control. 1993; 4: 123-132
        • Vaughan T.L.
        • Davis S.
        • Kristal A.
        • et al.
        Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma.
        Cancer Epidemiol Biomarkers Prev. 1995; 4: 85-92
        • Blot W.J.
        Alcohol and cancer.
        Cancer Res. 1992; 52: 2119s-2123s
        • Garro A.J.
        • Lieber C.S.
        Alcohol and cancer.
        Annu Rev Pharmacol Toxicol. 1990; 30: 219-249
        • Brown L.M.
        • Hoover R.
        • Silverman D.
        • et al.
        Excess incidence of squamous cell esophageal cancer among US Black men: role of social class and other risk factors.
        Am J Epidemiol. 2001; 153: 114-122
        • Chyou P.H.
        • Nomura A.M.
        • Stemmermann G.N.
        Diet, alcohol, smoking and cancer of the upper aerodigestive tract: a prospective study among Hawaii Japanese men.
        Int J Cancer. 1995; 60: 616-621
        • Gammon M.D.
        • Schoenberg J.B.
        • Ahsan H.
        • et al.
        Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia.
        J Natl Cancer Inst. 1997; 89: 1277-1284
        • Kneller R.W.
        • McLaughlin J.K.
        • Bjelke E.
        • et al.
        A cohort study of stomach cancer in a high-risk American population.
        Cancer. 1991; 68: 672-678
        • Stinson F.S.
        • Lane J.D.
        • Williams G.D.
        • Dufour M.C.
        U.S. Apparent consumption of alcoholic beverages. U.S. alcohol epidemiologic data reference manual. 3rd edition. National Institute on Alcohol Abuse and Alcoholism, Division of Biometry and Epidemiology, Rockville (MD)1997 (p. 1)
        • Caetano R.
        • Clark C.L.
        Trends in alcohol consumption patterns among whites, blacks and Hispanics: 1984 and 1995.
        J Stud Alcohol. 1998; 59: 659-668
        • Johnson R.C.
        • Nagoshi C.T.
        Asians, Asian-Americans and alcohol.
        J Psychoactive Drugs. 1990; 22: 45-52
        • Brown L.M.
        • Blot W.J.
        • Schuman S.H.
        • et al.
        Environmental factors and high risk of esophageal cancer among men in coastal South Carolina.
        J Natl Cancer Inst. 1988; 80: 1620-1625
        • Mettlin C.
        • Graham S.
        • Priore R.
        • et al.
        Diet and cancer of the esophagus.
        Nutr Cancer. 1981; 2: 143-147
        • Pottern L.M.
        • Morris L.E.
        • Blot W.J.
        • et al.
        Esophageal cancer among black men in Washington, D.C..
        J Natl Cancer Inst. 1981; 67: 777-783
        • Yu M.C.
        • Garabrant D.H.
        • Peters J.M.
        • et al.
        Tobacco, alcohol, diet, occupation, and carcinoma of the esophagus.
        Cancer Res. 1988; 48: 3843-3848
        • International Agency for Research on Cancer
        Tobacco smoking.
        in: IARC Monographs of the Evaluation of the Carcinogenic Risk of Chemicals to Humans. vol. 38. International Agency for Research on Cancer, Lyon, France1986
        • Brown L.M.
        • Hoover R.N.
        • Greenberg R.S.
        • et al.
        Are racial differences in squamous cell esophageal cancer explained by alcohol and tobacco use?.
        J Natl Cancer Inst. 1994; 86: 1340-1345
        • Nomura A.
        Stomach cancer.
        in: Schottenfeld D. Fraumeni Jr., J.F. Cancer epidemiology and prevention. 2nd edition. Oxford University Press, New York1996: 707-724
        • Wu-Williams A.H.
        • Yu M.C.
        • Mack T.M.
        Life-style, workplace, and stomach cancer by subsite in young men of Los Angeles County.
        Cancer Res. 1990; 50: 2569-2576
        • Centers for Disease Control and Prevention
        Cigarette smoking among adults in United States, 1998.
        Morb Mortal Wkly Rep. 2000; 49: 881-884
        • National Center for Health Statistics
        Health, United States, 2000, with Adolescent Health Chartbook. NCHS, Hyattsville (MD)2000
        • Fiore M.C.
        Trends in cigarette smoking in the United States. The epidemiology of tobacco use.
        Med Clin North Am. 1992; 76: 289-303
        • Barone J.
        • Taioli E.
        • Hebert J.R.
        • et al.
        Vitamin supplement use and risk for oral and esophageal cancer.
        Nutr Cancer. 1992; 18: 31-41
        • Block G.
        Vitamin C and cancer prevention: the epidemiologic evidence.
        Am J Clin Nutr. 1991; 53 ([comments]): 270S-282S
        • Brown L.M.
        • Swanson C.A.
        • Gridley G.
        • et al.
        Adenocarcinoma of the esophagus: role of obesity and diet.
        J Natl Cancer Inst. 1995; 87: 104-109
        • Brown L.M.
        • Swanson C.A.
        • Gridley G.
        • et al.
        Dietary factors and the risk of squamous cell esophageal cancer among black and white men in the United States.
        Cancer Causes Control. 1998; 9: 467-474
        • Galanis D.J.
        • Kolonel L.N.
        • Lee J.
        • et al.
        Intakes of selected foods and beverages and the incidence of gastric cancer among the Japanese residents of Hawaii: a prospective study.
        Int J Epidemiol. 1998; 27: 173-180
        • Harrison L.E.
        • Zhang Z.F.
        • Karpeh M.S.
        • et al.
        The role of dietary factors in the intestinal and diffuse histologic subtypes of gastric adenocarcinoma: a case-control study in the U.S.
        Cancer. 1997; 80: 1021-1028
        • Zhang Z.F.
        • Kurtz R.C.
        • Yu G.P.
        • et al.
        Adenocarcinomas of the esophagus and gastric cardia: the role of diet.
        Nutr Cancer. 1997; 27: 298-309
        • Ziegler R.G.
        • Morris L.E.
        • Blot W.J.
        • et al.
        Esophageal cancer among black men in Washington, D.C..
        J Natl Cancer Inst. 1981; 67: 1199-1206
        • Steinmetz K.A.
        • Potter J.D.
        Vegetables, fruit, and cancer prevention: a review.
        J Am Diet Assoc. 1996; 96: 1027-1039
        • Hargreaves M.K.
        • Baquet C.
        • Gamshadzahi A.
        Diet, nutritional status, and cancer risk in American blacks.
        Nutr Cancer. 1989; 12: 1-28
        • Swanson C.A.
        • Gridley G.
        • Greenberg R.S.
        • et al.
        A comparison of diets of blacks and whites in three areas of the United States.
        Nutr Cancer. 1993; 20: 153-165
        • Putnam J.J.
        • Allshouse J.E.
        Food consumption, prices, and expenditures, 1970–1997. Statistical Bulletin No. 965. Economic Research Service. US Department of Agriculture, Washington (DC)1999
        • Gridley G.
        • McLaughlin J.K.
        • Blot W.J.
        Dietary vitamin C intake and cigarette smoking.
        Am J Public Health. 1990; 80 ([letter]): 1526
        • Chow W.H.
        • Blot W.J.
        • Vaughan T.L.
        • et al.
        Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia.
        J Natl Cancer Inst. 1998; 90: 150-155
        • Nomura A.M.
        • Stemmermann G.N.
        • Chyou P.H.
        Gastric cancer among the Japanese in Hawaii.
        Jpn J Cancer Res. 1995; 86: 916-923
        • Gorey K.M.
        • Vena J.E.
        Cancer differentials among US blacks and whites: quantitative estimates of socioeconomic-related risks.
        J Natl Med Assoc. 1994; 86: 209-215
        • Ernster V.L.
        • Selvin S.
        • Sacks S.T.
        • et al.
        Major histologic types of cancers of the gum and mouth, esophagus, larynx, and lung by sex and by income level.
        J Natl Cancer Inst. 1982; 69: 773-776
        • U.S. Bureau of the Census
        Measuring 50 years of economic change using the march current population survey. US Government Printing Office, Washington (DC)1998 (p. 60–203)
        • Garewal H.S.
        • Sampliner R.
        Barrett's esophagus: a model premalignant lesion for adenocarcinoma.
        Prev Med. 1989; 18: 749-756
        • Spechler S.J.
        • Goyal R.K.
        Barrett's esophagus.
        N Engl J Med. 1986; 315: 362-371
        • Cohen S.
        • Parkman H.P.
        Heartburn—a serious symptom.
        N Engl J Med. 1999; 340: 878-879
        • Chow W.H.
        • Finkle W.D.
        • McLaughlin J.K.
        • et al.
        The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia.
        JAMA. 1995; 274: 474-477
        • Farrow D.C.
        • Vaughan T.L.
        • Sweeney C.
        • et al.
        Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer.
        Cancer Causes Control. 2000; 11: 231-238
        • Blaser M.J.
        • Perez-Perez G.I.
        • Kleanthous H.
        • et al.
        Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.
        Cancer Res. 1995; 55: 2111-2115
        • Fox J.G.
        • Wang T.C.
        Helicobacter pylori—not a good bug after all!.
        N Engl J Med. 2001; 345: 829-832
        • IARC Working Group
        Schistosomes, liver flukes, and Helicobacter pylori.
        in: IARC Monographs of the Evaluation of Carcinogenic Risks to Humans. 61. International Agency for Research on Cancer, Lyon, France1994: 177-241
        • Chow W.H.
        • Blaser M.J.
        • Blot W.J.
        • et al.
        An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma.
        Cancer Res. 1998; 58: 588-590
        • Blaser M.J.
        Hypothesis: the changing relationships of Helicobacter pylori and humans: implications for health and disease.
        J Infect Dis. 1999; 179: 1523-1530