Local Excision and Endoscopic Strategies for the Treatment of Colorectal Cancer

Published:March 09, 2022DOI:


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.


      Subscribe to Surgical Oncology Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Zauber A.G.
        • Winawer S.J.
        • O’Brien M.J.
        • et al.
        Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths.
        N Engl J Med. 2012; 366: 687-696
        • Patel S.G.
        • Boland C.R.
        Colorectal cancer in persons under age 50: seeking causes and solutions.
        Gastrointest Endosc Clin N Am. 2020; 30: 441-455
        • Kaltenbach T.
        • Anderson J.C.
        • Burke C.A.
        • et al.
        Endoscopic removal of colorectal lesions-recommendations by the US multi-society task force on colorectal cancer.
        Gastroenterology. 2020; 158: 1095-1129
        • Peery A.F.
        • Cools K.S.
        • Strassle P.D.
        • et al.
        Increasing rates of surgery for patients with nonmalignant colorectal polyps in the United States.
        Gastroenterology. 2018; 154: 1352-1360.e3
        • Gorgun E.
        • Benlice C.
        • Abbas M.A.
        • et al.
        Experience in colon sparing surgery in North America: advanced endoscopic approaches for complex colorectal lesions.
        Surg Endosc. 2018; 32: 3114-3121
        • Stevenson A.R.L.
        • Solomon M.J.
        • Brown C.S.B.
        • et al.
        Disease-free survival and local recurrence after laparoscopic-assisted resection or open resection for rectal cancer: the Australasian Laparoscopic Cancer of the rectum randomized clinical trial.
        Ann Surg. 2019; 269: 596-602
        • Fleshman J.
        • Branda M.E.
        • Sargent D.J.
        • et al.
        Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer: follow-up results of the ACOSOG Z6051 randomized controlled trial.
        Ann Surg. 2019; 269: 589-595
        • Lacy A.M.
        • Tasende M.M.
        • Delgado S.
        • et al.
        Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients.
        J Am Coll Surg. 2015; 221: 415-423
      1. Robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial.
        JAMA. 2017; 318: 1569-1580
        • Moss A.
        • Bourke M.J.
        • Williams S.J.
        • et al.
        Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia.
        Gastroenterology. 2011; 140: 1909-1918
        • Saito Y.
        • Uraoka T.
        • Yamaguchi Y.
        • et al.
        A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video).
        Gastrointest Endosc. 2010;
        • Scheele J.
        • Schmidt S.A.
        • Tenzer S.
        • et al.
        Overstaging: a challenge in rectal cancer treatment.
        Visc Med. 2018; 34: 301-306
        • Salinas H.M.
        • Dursun A.
        • Klos C.L.
        • et al.
        Determining the need for radical surgery in patients with T1 rectal cancer.
        Arch Surg. 2011; 146: 540-543
      2. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002.
        Gastrointest Endosc. 2003; 58: S3-S43
        • Kudo S.
        • Tamura S.
        • Nakajima T.
        • et al.
        Diagnosis of colorectal tumorous lesions by magnifying endoscopy.
        Gastrointest Endosc. 1996; 44: 8-14
        • Hayashi N.
        • Tanaka S.
        • Hewett D.G.
        • et al.
        Endoscopic prediction of deep submucosal invasive carcinoma: validation of the Narrow-Band Imaging International Colorectal Endoscopic (NICE) classification.
        Gastrointest Endosc. 2013;
        • Habr-Gama A.
        • Perez R.O.
        • Nadalin W.
        • et al.
        Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results.
        Ann Surg. 2004; 240: 711-718
        • Perez R.O.
        • Habr-Gama A.
        • Sao Juliao G.P.
        • et al.
        Transanal endoscopic microsurgery for residual rectal cancer after neoadjuvant chemoradiation therapy is associated with significant immediate pain and hospital readmission rates.
        Dis Colon Rectum. 2011; 54: 545-551
        • Garcia-Aguilar J.
        • Mellgren A.
        • Sirivongs P.
        • et al.
        Local excision of rectal cancer without adjuvant therapy: a word of caution.
        Ann Surg. 2000; 231: 345-351
        • Madbouly K.M.
        • Remzi F.H.
        • Erkek B.A.
        • et al.
        Recurrence after transanal excision of T1 rectal cancer: should we be concerned?.
        Dis Colon Rectum. 2005; 48: 711-721
        • Wang J.
        • Zhang X.H.
        • Ge J.
        • et al.
        Endoscopic submucosal dissection vs endoscopic mucosal resection for colorectal tumors: a meta-analysis.
        World J Gastroenterol. 2014;
        • Repici A.
        • Hassan C.
        • De Paula Pessoa D.
        • et al.
        Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review.
        Endoscopy. 2012;
        • Sapci I.
        • Gorgun E.
        Endoscopic submucosal dissection.
        in: Bardakcioglu O. Advanced techniques in minimally invasive and robotic colorectal surgery. Springer, Cham2019: 9-16
        • Sanchez-Yague A.
        • Kaltenbach T.
        • Raju G.
        • et al.
        Advanced endoscopic resection of colorectal lesions.
        Gastroenterol Clin North Am. 2013;
        • Nugent E.
        • Sapci I.
        • Steele S.R.
        • et al.
        Pushing the envelope in endoscopic submucosal dissection: is it feasible and safe in scarred lesions?.
        Dis Colon Rectum. 2021; 64: 343-348
        • Sapci I.
        • Gorgun E.
        Removal of a large rectal lesion with endoscopic submucosal dissection using a new endolumenal platform.
        Dis Colon Rectum. 2020; 63: 710
        • De Ceglie A.
        • Hassan C.
        • Mangiavillano B.
        • et al.
        Endoscopic mucosal resection and endoscopic submucosal dissection for colorectal lesions: a systematic review.
        Crit Rev Oncol Hematol. 2016; 104: 138-155
        • Akintoye E.
        • Kumar N.
        • Aihara H.
        • et al.
        Colorectal endoscopic submucosal dissection: a systematic review and meta-analysis.
        Endosc Int Open. 2016; 4: E1030-E1044
        • Gupta S.
        • Lieberman D.
        • Anderson J.C.
        • et al.
        Recommendations for follow-up after colonoscopy and polypectomy: a consensus update by the US multi-society task force on colorectal cancer.
        Am J Gastroenterol. 2020; 115: 415-434
        • Pimentel-Nunes P.
        • Dinis-Ribeiro M.
        • Ponchon T.
        • et al.
        Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) guideline.
        Endoscopy. 2015; 47: 829-854
        • Tanaka S.
        • Kashida H.
        • Saito Y.
        • et al.
        Japan Gastroenterological Endoscopy Society guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection.
        Dig Endosc. 2020; 32: 219-239
        • Belderbos T.D.
        • Leenders M.
        • Moons L.M.
        • et al.
        Local recurrence after endoscopic mucosal resection of nonpedunculated colorectal lesions: systematic review and meta-analysis.
        Endoscopy. 2014; 46: 388-402