Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Surgical Oncology ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The Cancer Genome Atlas Program - National Cancer Institute [Internet].(Available at:) (Accessed August 26, 2021)
- The Cancer Genome Atlas - Timeline and Milestones - National Cancer Institute [Internet].(Available at:)https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga/history/timeline(Accessed August 26, 2021)
- The Cancer Genome Atlas - Molecular Characterization Platforms - National Cancer Institute [Internet].(Available at:) (Accessed September 20, 2021)
- The Cancer Genome Atlas - Publications - National Cancer Institute [Internet].(Available at:) (Accessed August 26, 2021)
- The Cancer Genome Atlas - Cancers Selected for Study - National Cancer Institute [Internet].(Available at:) (Accessed August 26, 2021)
- Soft tissue sarcoma: an update on systemic treatment options for patients with advanced disease.Oncol Res Treat. 2014; 37: 355-362
- UK guidelines for the management of soft tissue sarcomas.Clin Sarcoma Res. 2016; 6: 1-26
- Comprehensive and integrated genomic characterization of adult soft tissue sarcomas.Cell. 2017; 171: 950-965.e28
- Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials.Lancet Oncol. 2018; 19: 416-426
- Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.Lancet Oncol. 2017; 18: 1493-1501
- 796 A phase I/II trial combining avelumab and trabectedin for advanced liposarcoma and leiomyosarcoma.J Immunother Cancer. 2020; 8: A844
- WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition.Pathology. 2014; 46: 95-104
- Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling.Oncogene. 2010; 29: 845-854
- Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.Nat Commun. 2021; 12: 1-14
- Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.Lancet. 2012; 379: 1879-1886
- State of the Field in Multi-Omics Research: From Computational Needs to Data Mining and Sharing.Front Genet. 2020; 0: 1598
- Data integration in the era of omics: current and future challenges.BMC Syst Biol. 2014; 8: 1-10
- Metabolomics in cancer research and emerging applications in clinical oncology.CA Cancer J Clin. 2021; 71: 333-358
- Phosphoproteomics in translational research: a sarcoma perspective.Ann Oncol. 2016; 27: 787-794
- Proteomic research in sarcomas – current status and future opportunities.Semin Cancer Biol. 2020; 61 (Academic Press): 56-70
- A comprehensive map of molecular drug targets.Nat Rev Drug Discov. 2017; 16: 19
- Clinical Proteomic Tumor Analysis Consortium (CPTAC) | NCI Genomic Data Commons [Internet].(Available at:) (Accessed October 12, 2021)
- Identification of microRNA biomarkers for response of advanced soft tissue sarcomas to eribulin: Translational results of the EORTC 62052 trial.Eur J Cancer. 2017; 75: 33-40
- Future treatment of soft tissue sarcomas will be driven by histological subtype and molecular aberrations.Eur J Cancer. 2010; 46: 863-868
- Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors.Am J Surg Pathol. 2000; 24: 937-946
- Diagnosis and management of tropomyosin receptor kinase (TRK) fusion sarcomas: expert recommendations from the World Sarcoma Network.Ann Oncol. 2020; 31: 1506-1517
- The Genomic Grade Index predicts postoperative clinical outcome in patients with soft-tissue sarcoma.Ann Oncol. 2018; 29: 459-465
- Validation of the Complexity INdex in SARComas prognostic signature on formalin-fixed, paraffin-embedded, soft-tissue sarcomas.Ann Oncol. 2018; 29: 1828-1835
- Predictive and prognostic transcriptomic biomarkers in soft tissue sarcomas.NPJ Precis Oncol. 2021; 5
- Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.Immunity. 2013; 39: 782-795
- B cells are associated with survival and immunotherapy response in sarcoma.Nat. 2020; 577: 556-560
- Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.Ann Oncol Off J Eur Soc Med Oncol. 2018; 29: iv51-iv67
- Development and external validation of two nomograms to predict overall survival and distant metastases after surgical resection of localised soft tissue sarcomas of the extremities: a retrospective analysis.Lancet Oncol. 2016; 17: 671-680
- Development and external validation of a dynamic prognostic nomogram for primary extremity soft tissue sarcoma survivors.EClinicalMedicine. 2019; 17: 100215
- The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomized trial.Eur J Cancer. 2019; 109: 51-60
- Neoadjuvant chemotherapy in high risk soft tissue sarcomas: a sarculator-based risk stratification analysis of the randomized trial ISG-STS 1001.Cancer. 2022; 128: 85-93
NCT03449901. https://www.clinicaltrials.gov/ct2/show/NCT03449901?term=brian+van+tine&draw=3&rank=22.
- Arginine Starvation and Docetaxel Induce c-Myc–Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors.Clin Cancer Res. 2019; 25: 5122-5134
Article info
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.